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Mary’s award-winning transdermal patches are born out of a commitment to accurate dosing through an advanced delivery method. The 2”x2” squares simply adhere to any venous part of the skin for 8-12 hours of unsurpassed, systemic relief. -Discreet, convenient and reliable -Apply to any venous area of the skin for best results -Provides 8-12 hours of unsurpassed, systemic relief -High bioavailability -15-30-minute uptake time